Information | |
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has gloss | eng: An anxiogenic substance is one that causes anxiety. Anxiogenic effects can be measured by, for example, the hole-board test in rats and mice. A number of agents are used to provoke anxiety (anxiogens) or panic (panicogens) in experimental models . Some of the most common substances are: sodium lactate, carbon dioxide (as carbogen), L-DOPA, caffeine, GABA antagonists such as DMCM, FG-7142 and ZK-93426, serotonergic agents such as mCPP, adrenergic agents such as yohimbine, and cholecystokinin (CCK) (especially the tetrapeptide and octapeptide fragments CCK-4 and CCK-8). Studies have shown that 10 mL/kg of 0.5 molar sodium lactate infused intravenously over a 20-minute period will provoke a panic attack in most patients with panic disorder but not healthy control subjects. |
lexicalization | eng: anxiogenic |
instance of | (noun) a drug that can produce mood changes and distorted perceptions psychoactive drug, psychoactive substance, consciousness-altering drug, mind-altering drug |
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Polish | |
has gloss | pol: Anksjogeniki (substancje anksjogenne) – substancje psychotropowe powodujące nasilenia się poczucia lęku i niepokoju. Używane są w wywoływaniu lęku u zwierząt laboratoryjnych. Część tych substancji powoduje uczucie lekkiego niepokoju, inne mogą powodować pojawienie się napadu paniki. Do anksjogeników zalicza się: |
lexicalization | pol: Anksjogeniki |
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