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has gloss | eng: Cinacalcet (INN) is a drug that acts as a calcimimetic (i.e. it mimics the action of calcium on tissues) by allosteric activation of the calcium-sensing receptor that is expressed in various human organ tissues. It is sold by Amgen under the trade name Sensipar in North America and Australia and as Mimpara in Europe. Cinacalcet is used to treat secondary hyperparathyroidism (elevated parathyroid hormone levels), a consequence of having end-stage renal disease. . Cinacalcet is also indicated for the treatment of hypercalcemia in patients with parathyroid carcinoma. |
lexicalization | eng: Cinacalcet |
instance of | (noun) (chemistry) a substance formed by chemical union of two or more elements or ingredients in definite proportion by weight chemical compound, compound |
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German | |
has gloss | deu: Cinacalcet ist eine chirale organische chemische Verbindung aus der Gruppe der Naphthalin-Derivate. Die fluorhaltige Verbindung wurde von Amgen entwickelt und wird als Arzneistoff in der Therapie des sekundären Hyperparathyreoidismus – einer Erkrankung der Nebenschilddrüse – eingesetzt. |
lexicalization | deu: Cinacalcet |
Polish | |
has gloss | pol: Cynakalcet (łac. cinacalcetum) – lek kalcymimetyczny, obniżający stężenie parathormonu we krwi . __TOC__ |
lexicalization | pol: cynakalcet |
Media | |
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media:img | Cinacalcet Structural Formulae.png |
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