e/Methylated DNA immunoprecipitation

New Query

Information
has glosseng: Methylated DNA immunoprecipitation (MeDIP or mDIP) is a large-scale (chromosome- or genome-wide) technique that is used to enrich for methylated DNA sequences. It consists of isolating methylated DNA fragments via an antibody raised against 5-methylcytosine (5mC). This technique was first described by Weber M. et al. and has helped pave the way for viable methylome-level assessment efforts, as the purified fraction of methylated DNA can be input to high-throughput DNA detection methods such as high-resolution DNA microarrays (MeDIP-chip) or next-generation sequencing (MeDIP-seq). Nonetheless, understanding of the methylome remains rudimentary; its study is complicated by the fact that, like other epigenetic properties, patterns vary from cell-type to cell-type.
lexicalizationeng: Methylated DNA immunoprecipitation
instance ofe/Protein methods
Media
media:imgLog2R.jpg
media:imgMedip-final-3.jpg
media:imgStudy-flow.jpg

Query

Word: (case sensitive)
Language: (ISO 639-3 code, e.g. "eng" for English)


Lexvo © 2008-2025 Gerard de Melo.   Contact   Legal Information / Imprint