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has gloss | (noun) tumor of the fibrous covering of a peripheral nerve neurofibroma, neurilemoma |
has gloss | eng: A neurofibroma is a benign nerve sheath tumor in the peripheral nervous system. Usually found in individuals with neurofibromatosis type 1 (NF1), a genetically-inherited disease, they can result in a range of symptoms from physical disfiguration and pain to cognitive disability. Neurofibromas arise from Schwann cells that exhibit biallelic inactivation of the NF1 gene that codes for the protein neurofibromin. This protein is responsible for regulating the RAS-mediated cell growth pathway. In contrast to schwannomas, another type of tumor arising from Schwann cells, neurofibromas incorporate many additional types of cells and structural elements in addition to Schwann cells, making it difficult to identify and understand all the mechanisms through which they originate and develop. |
lexicalization | eng: neurilemoma |
lexicalization | eng: neurofibroma |
subclass of | (noun) an abnormal new mass of tissue that serves no purpose tumour, tumor, neoplasm |
Meaning | |
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Catalan | |
lexicalization | cat: neurofibroma |
Mandarin Chinese | |
lexicalization | cmn: shén jīng xiān wéi liu |
lexicalization | cmn: 神經纖維瘤 |
lexicalization | cmn: 神经纤维瘤 |
German | |
has gloss | deu: Neurofibrome sind Nerventumore, die innerhalb des Nervs gut abgrenzbare oder außerhalb des Nervs diffuse Strukturen ausbilden. Sie bestehen aus neoplastischen Schwann-Zellen, Fibroblasten und perineuralen Zellen, die in eine Matrix aus Kollagenfasern eingebettet sind. Sie werden auf der WHO-Skala von I-IV mit der Stufe I klassifiziert. Vom Schwannom unterscheiden sie sich durch einen höheren Gehalt an bindegewebiger Substanz und dadurch, dass sie operativ nicht von den Nerven getrennt werden können und diese in der Regel geopfert werden müssen. |
lexicalization | deu: Neurofibrom |
Lithuanian | |
has gloss | lit: Neurofibroma (neuron ir – skaidula) – nepiktybinis periferinių nervų auglys. |
lexicalization | lit: neurofibroma |
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similar | e/Neurofibroma |
Media | |
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media:img | Neurofibroma (1).jpg |
media:img | Neurofibroma.png |
media:img | Neurofibroma02.jpg |
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