e/Dibucaine number

Information
has gloss	eng: Dibucaine Number, also known as cinchocaine, is an amino amide local anesthetic. It is commonly used as an agent for central neuraxial anesthesia in Great Britain. When administered to humans intravenously, it is capable of inhibiting the plasma cholinesterase enzyme (E.C.3.1.1.8). This tetrameric enzyme is responsible for the metabolism of a number of substances including amino ester local anesthetics and succinylcholine. Plasma cholinesterase is also known as butyrylcholinesterase, in part because once an individual is given butyrylcholine intravenously, the enzyme converts it to the products succinylmonocholine and choline. Dibucaine inhibits normal butyrylcholinesterase activity, reducing the ability to convert butyrylcholine to its byproducts. The extent of the catalysis can be determined by measuring the percentage of butyrylcholine that remains unchanged in the blood of individuals administered a standard dose after dibucaine inhibition challenge in what has been established as the Dibucaine Number test.
lexicalization	eng: dibucaine number
instance of	e/Local anesthetic