e/Pumiliotoxin

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has glosseng: Pumiliotoxins (PTXs), are one of several toxins found in the skin of poison dart frogs. Closely related, though more toxic, are allopumiliotoxins, (aPTXs). Other toxins found in the skin of poison frogs include decahydroquinolines (DHQs), izidines, coccinellines, and spiropyrrolizidines. Pumiliotoxins are very poisonous in high concentration. Pumiliotoxins are much weaker than that of the batrachotoxins, they can be between 100-1000 times weaker. There are three different types of this toxin A, B and C. Toxins A and B are a lot more toxic than C. Pumiliotoxins affect the body because they interfere with muscle contraction in the heart and skeletal muscle. The toxin works by affecting the calcium channels. Some of the symptoms of pumiliotoxins are partial paralysis, having difficulty moving, being hyperactive and in some cases it can result in death.
lexicalizationeng: Pumiliotoxin
instance of(noun) natural bases containing nitrogen found in plants
alkaloid
Meaning
German
has glossdeu: Pumiliotoxine gehören zu den intensiv wirkenden Alkaloiden. Pumiliotoxine finden sich in den Hautdrüsen des Erdbeerfröschchen (Dendrobates pumilio), der in den Wäldern Panamas beheimatet ist. Derzeit hat man bei der Familie der Pfeilgiftfrösche ca. 200 verschiedene, zum Teil äußerst giftige Alkaloide entdeckt, die auch für den Menschen tödlich sein können (siehe Pfeilgiftfrösche).
lexicalizationdeu: Pumiliotoxine
Japanese
has glossjpn: プミリオトキシン類 (pumiliotoxins, PTXs) はインドリジン骨格を有するアルカロイドの一種。ヤドクガエルに含まれる毒物で、より強毒性の類縁体としてアロプミリオトキシン類 (allopumiliotoxin, aPTXs) やプリミオトキシン251Dがある。ヤドクガエルに含まれる毒物としては他に、デカヒドロキノリン (DHQ) やizidine、コッシネリン (coccinelline) スピロピロリジジン (spiropyrrolizidine) などがある。高濃度のプミリオトキシンは高い毒性を示すが、毒性の強さはバトラコトキシン (batrachotoxin) の100-1000倍程度弱い。
lexicalizationjpn: プミリオトキシン
Dutch
has glossnld: Pumiliotoxines vormen een groep van ca. 80 aanverwante zeer giftige chemische verbindingen (alkaloïden) die onder andere worden aangetroffen in de huid van pijlgifkikkers (Dendrobatidae). Andere stoffen die zich in de huid van pijlgifkikkers bevinden zijn decahydroquinolines, izidines, coccinellines en spiropyrrolizidines. Pumiliotoxines zijn niet altijd dodelijk, maar kunnen zowel fysische als psychische letsels veroorzaken.
lexicalizationnld: pumiliotoxine
Media
media:imgPumiliotoxin AB.svg
media:imgPumiliotoxin C.png
media:imgPumiliotoxin251D.png

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