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| has gloss | eng: The vault or vault cytoplasmic ribonucleoprotein is a eukaryotic organelle whose function is not fully understood. Discovered and successfully isolated by cell biologist Nancy Kedersha and biochemist Leonard Rome of the UCLA School of Medicine in the 1980s, vaults are cytoplasmic organelles which under an electron microscope resemble the arches of a cathedral vault, with 39-fold symmetry (Tanaka, et al. Science 16 January 2009: Vol. 323. no. 5912, pp. 384 - 388). They are present in many types of eukaryotic cells and appear to be highly conserved amongst eukaryotes. . Vaults become part of lipid rafts where they may play a role fighting pathogens. Vault RNA contains Vault proteins. |
| lexicalization | eng: vault |
| instance of | (noun) a specialized part of a cell; analogous to an organ; "the first organelle to be identified was the nucleus" organelle, cell organ, cell organelle |
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| Italian | |
| has gloss | ita: Il Vault è un organulo presente nelle cellule eucariote la cui funzione non è ancora completamente conosciuta. Fu scoperto e successivamente isolato dalla biologa Nancy Kadersha e dal biochimico Leonard Rome della " UCLA School of Medicine " negli anni '80. I vault sono organuli citoplasmatici che devono il loro nome alla loro somiglianza con le volte di una cattedrale. Sono presenti in molti tipi di cellule eucariote e sembrerebbe che essi si siano ben conservati tra gli eucarioti . I vault possono far parte delle zattere lipidiche nelle quali possono svolgere un ruolo di difesa contro agenti patogeni . |
| lexicalization | ita: vault |
| Japanese | |
| has gloss | jpn: ヴォールト（vault、またはヴォールト細胞質リボヌクレオタンパク質 vault cytoplasmic ribonucleoprotein）は真核生物に見られる細胞小器官で、その機能はまだ完全には分かっていない。1980年代にUCLA薬学部の細胞生物学者ナンシー・ケデルシャ（Nancy Kedersha）と生化学者レオナルド・ロメ（Leonard Rome）が発見し単離した。電子顕微鏡で見ると大聖堂のアーチに似た形をした細胞質にある小器官で、39個の対称要素が対称に２つ配置されてできている。(Tanaka, et al. Science 16 January 2009: Vol. 323. no. 5912, pp. 384 - 388) 様々な種類の真核生物細胞で見られ、真核生物間でその配列はよく保存されているようである 。 ヴォールトは病原体と闘う役割をしている可能性がある脂質ラフト（lipid raft）の一部となる 。ヴォールトRNAはヴォールトタンパク質を含む。 |
| lexicalization | jpn: ヴォールト |
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| media:img | 2zuo bio r 500.jpg |
| media:img | 2zuo bio r 500.png |
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